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Apigenin signi? cantly affectsHIF1? protein stability but also slightly down-regulates HIF1? mRNA, and againthis corresponds with down-regulation of Mdm2 [ 12]. CO is dependent on HR; hypotension manifests because of reduced COsecondary to bradycardia. Intracellular microtubules in thecells of the worm are gradually lost. ( 2001) with per-mission of the American Thoracic Society.
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