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Early in the DNA damage response, p53relays a wide range of pro-survival signals like cell cycle arrest allowing the cells torepair the damage. Theglycogen is conspicuous in Figure 15.18a because of itsamount; it would stain intensely with the periodic acid-Schiff (PAS) method. Then, theforce translates into pressure, the magnitude ofwhich depends on the geometrical characteristicsof the muscle and the structure over which theforce is applied. Magnussen CG buy modafinil in europe Berenson GS, Venn A,Burns TL, Sabin MA, et al. however, some migrate to the bone marrowand successfully compete for limited niches.