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The designation ofFTLD-UPS (ubiquitin–proteasome syndrome) now refersto cases with ubiquitin positivity that have not been linkedto a specific protein (such as familial syndrome of FTD3as a result of CHMP2B mutations; Mackenzie et al., 2009).In FTLD-TDP, brain atrophy is variable but may besevere, especially in frontotemporal distribution and thehippocampus, and there is associated dilation of the lat-eral ventricles

The designation ofFTLD-UPS (ubiquitin–proteasome syndrome) now refersto cases with ubiquitin positivity that have not been linkedto a specific protein (such as familial syndrome of FTD3as a result of CHMP2B mutations; Mackenzie et al., 2009).In FTLD-TDP, brain atrophy is variable but may besevere, especially in frontotemporal distribution and thehippocampus, and there is associated dilation of the lat-eral ventricles.

Position theclient’s hips toward the bottom of the examination table sothat the feet can rest comfortably in the stirrups.

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